Sinequan Withdrawal and Tapering Help

How Point of Return can Help You

The Point of Return Program is an in-home tapering program that allows you to gradually lessen the amount of Sinequan while also implementing the use of all-natural, calming nutraceuticals to ease symptoms. Sinequancan be dangerous to abruptly or rapidly stop and our program is a proven, viable, low-cost option to continue living your life while tapering.

Click here for more information about our antidepressant tapering program.

Sinequan Withdrawal Symptoms May Include:

aggression, anxiety, balance issues , blurred vision, brain zaps, concentration impairment, constipation, crying spells, depersonalization, diarrhea, dizziness. electric shock sensations, fatigue, flatulence, flu-like symptoms, hallucinations, hostility, highly emotional, indigestion, irritability, impaired speech, insomnia, jumpy nerves, lack of coordination, lethargy, migraine headaches / increased headaches, nausea, nervousness, over-reacting to situations, paranoia, repetitive thoughts or songs, sensory & sleep disturbances, severe internal restlessness (akathisia), stomach cramps, tremors, tinnitus (ear ringing or buzzing), tingling sensations, troubling thoughts, visual hallucinations / illusions, vivid dreams, speech or visual changes, worsened depression

Sinequan Side Effects May Include:

drowsiness, Blurred vision, breast development in males, bruises, buzzing or ringing in the ears, changes in sex drive, chills, confusion, constipation, diarrhea, difficulty urinating, disorientation, dizziness, dry mouth, enlarged breasts, fatigue, fluid retention, flushing, fragmented or incomplete movements, hair loss, hallucinations, headache, high fever, high or low blood sugar, inappropriate breast milk secretion, indigestion, inflammation of the mouth, itching and skin rash, lack of muscle control, loss of appetite, loss of coordination, low blood pressure, nausea, nervousness, numbness, poor bladder control, rapid heartbeat, red or brownish spots on the skin, seizures, sensitivity to light, severe muscle stiffness, sore throat, sweating, swelling of the testicles, taste disturbances, tingling sensation, tremors, vomiting, weakness, weight gain, yellow eyes and skin

Other Names for Sinequan Include:(Doxepin, Aponal, Adapin, Deptran, Sinquan, Silenor)

History & Info
Sinequan (Doxepin) is a psychotropic agent with antidepressant and anti-anxiety properties that was developed by Boehringer-Ingelheim, now part of the Roche group. Sinequan was tested from 1963-1968 in different German and Swiss psychiatric institutions and was approved in Germany initially, then in other countries.

Sinequan is a Tricyclic Antidepressant that exerts its action on Serotonin and Norepinephrine but also blocks Dopamine and the histamine receptors. Histamine is involved in the immune response and Dopamine is a critical neurotransmitter that plays important roles in both the brain and body.  Serotonin is primarily found in the gastrointestinal tract, central nervous system and in the blood platelets while Norepinephrine works as both a hormone and a neurotransmitter, stimulating the heart, sweat glands, blood vessels, large internal organs and the adrenals whereas Serotonin is involved in sleep, memory, regulation of the endocrine system, body temperature, mood and behavior and muscle movement.

A study published in JAMA internal Medicine in early 2015 found Sinequan increased the risk of developing dementia.

Because Sinequan also blocks the neurotransmitter Acetylcholine, it is not recommended for patients with a history of glaucoma, increased intraocular pressure or urinary retention. Like all Tricyclic antidepressants, when given in high doses, Sinequan can induce sinus tachycardia, changes in conduction time and arrhythmias of the heart. A few instances of unexpected death have been reported in patients with cardiovascular disorders. Myocardial infarction and stroke have also been reported with drugs of this class. Therefore, Sinequan should be administered with extreme caution to patients with a history of cardiovascular disease, those with circulatory issues and elderly patients. Since Tricyclic agents are known to reduce the seizure threshold, Sinequan should be used with caution in patients with a history of convulsive disorders.

All Antidepressants can cause withdrawal symptoms if abruptly stopped or tapered too rapidly and Sinequan is no different. Treatment should not be suddenly or rapidly stopped, as withdrawal symptoms can be severe.  It is recommended to taper slowly yet many find that even a slow titration is extremely uncomfortable. 

This is why our team of experts use slow titration schedules combined with all-natural Nutraceuticals that will not interact with the medication but provide needed relief while tapering. This is a low-cost method with proven results.

Click here for more information on antidepressants...

    People We've Helped

    I am now sleeping GREAT and the nutrients has helped me with that!! It really, truly works!

    "First of all, I want to say there is hope for all of you who are going through a trial you feel will never end! I give glory to God for directing my path to Point of Return!" -Debbie H., (California) Temazepam, Paxil, Neurontin

    I am doing well and very excited to be antidepressant free

    "I found the program very helpful and will be forever grateful. Thank you from the bottom of my heart." -Dennis N., (Washington) Lexapro

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      DISCLAIMER: *Because prescription medications can cause severe withdrawal reactions, do not stop taking any medication without first consulting your physician. The decision to taper any medication should be discussed with your doctor and done with their consent and support.
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